Sounds like an issue with NVSE not running, did you apply the 4gb patch to the New Vegas exe or launch from the NVSE executable?
I had an issue awhile ago similar to this and it was because I had to restore the original exe for the TTW installer to run and forgot to change it back.
I had an issue awhile ago similar to this and it was because I had to restore the original exe for the TTW installer to run and forgot to change it back.
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