Tale of Two Wastelands

I followed the guide to the letter and get a black screen/console window CTD. I really really wish I could play this, especially over the holidays. I can't run vanilla FO3 or vanilla FNV anymore either, I suppose I will have to do yet another fresh install. If anyone has any suggestions I would love to hear them.
After the most recent update, my game started having issues.I was playing it all day, not a single issue.No new mods were added the game crashed I reload. And now my main menu screen has no options on it. No, matter what I do I cannot get it to work.